According to the Turner Syndrome Clinical Practice Guideline, “Fertility preservation is potentially feasible in women with TS, as many girls with TS have ovarian follicles until their late teens, and some women with mosaic TS have follicles for many years thereafter, even though they tend to experience early menopause. Oocyte cryopreservation after controlled ovarian hyperstimulation is a possible fertility preservation option in young mosaic TS women with persistent ovarian function. Case reports describe cryopreservation of 8–13 mature oocytes after controlled ovarian hyperstimulation in TS women aged 14–28 years. So far, there are no pregnancies reported after oocyte freezing and thawing in TS, as these women are still young and have not attempted pregnancy yet. Vitrification of oocytes at an even younger age, perhaps about 12 years, may be feasible, but so far, there are no reliable data in TS.” For the most current and appropriate options, please consult with your pediatric or adult Turner syndrome doctors.
According to the Turner Syndrome Clinical Practice Guideline, “Spontaneous or assisted pregnancy in TS should be undertaken only after thorough cardiac evaluation. Alarming reports of fatal aortic dissection during pregnancy and the postpartum period have raised concern about the safety of pregnancy in TS (65). If pregnancy is being considered, preconception assessment must include cardiology evaluation with MRI of the aorta. A history of surgically repaired cardiovascular defect, the presence of BAV, or current evidence of aortic dilatation or systemic hypertension should probably be viewed as relative contraindications to pregnancy. For those who become pregnant, close cardiology involvement throughout pregnancy and the postpartum period is essential.”
Increased maternal cardiovascular mortality associated with pregnancy in women with Turner syndrome 2012
Abstract Only: Turner’s syndrome and pregnancy: has the 45,X/47,XXX mosaicism a different prognosis? 2010 (Full Text Available for Download)
Serum Levels of Anti-Müllerian Hormone as a Marker of Ovarian Function in 926 Healthy Females from Birth to Adulthood and in 172 Turner Syndrome Patients 2010
Abstract Only Ovarian function and in vitro fertilization (IVF) in Turner syndrome 2012